What gets prescribed and why: Opioids v. obesity meds

By |2018-12-06T18:37:08+00:00December 6th, 2018|Chronic pain, Evidence-Based Medicine, Health Care Trends, Insurance, Uncategorized, What do we pay for and why|

What gets prescribed and why: Opioids v. obesity meds

The U.S. health care system doesn’t always make sense. Sometimes, even when there is some logic to it, the reasons underpinning what gets prescribed by practitioners and covered by insurers are disappointing. Two pieces I read recently provide examples.

In one study, we learn that while primary care physicians are prescribing opioids less often, other specialists and nurse practitioners are prescribing them more often. Ultimately, opioid prescribing remains at a high level, despite known issues with misuse and abuse, and the availability of alternative pain treatments.

At the same time, while 40% of U.S. adults are obese, fewer than 2% of obese patients are offered medications for obesity, and ultimately “only about 1% of eligible patients fill a prescription for a weight loss medication.” Even when weight loss medications are prescribed, it is usually for a specific (fairly short) period of time, explained Dr. Caroline M. Apovian, a Professor of Medicine and Pediatrics, Department of Medicine, Section of Endocrinology at Boston University School of Medicine and the Director of Nutrition and Weight Management, Department of Endocrinology, Diabetes, and Nutrition, at Boston Medical Center, in an opinion piece in Medscape.

This is an example of what we like to call at M2: “what do we pay for and why?” If 40% of the public has a disease, why aren’t treatments prescribed and covered? Several chronic obesity management medications have been approved by the U.S. Food and Drug Administration (FDA) in the past few years, and have proven of efficacy of 5%-10% weight loss, but Dr. Apovian argues that “public perception of obesity as a matter of will power rather than a disease” is a key barrier to lower treatment rates for obesity.

The U.S. health care system doesn’t necessarily pay for what works, or the treatments people need. As with all policy decisions, there is a judgment about who deserves what, and who should pay for it. In the case of treating obesity with a prescription, Dr. Apovian succinctly explains the current policy stance: “If obesity is considered a moral failing, why treat it with a pill or surgery?”

What’s the hold up? Why do physicians not turn more frequently to the known effective treatments for obesity? Well, sometimes it is lack of proper training (discussed in our in April). Physicians have a lot to stay up to date on, and obesity treatments are often not prioritized despite the prevalence of comorbidities. As we discussed in a back in February, improved insurance coverage for proven effective weight loss treatments could help avoid expensive complications from obesity down the road and may improve quality of life. We suggest this is a better way to choose what is covered the current approach.

Pain affects a large number of people in the U.S. as well – more than 100 million adults. Nearly 40 million adults experience the highest levels of pain (category 3 or category 4), and there are more than 25 million adults who report chronic (daily) pain. Further, the Centers for Disease Control and Prevention (CDC) Guideline for Prescribing Opioids for Chronic Pain is clear: “Opioids are not first-line or routine therapy for chronic pain.” Despite this clear recommendation, as the recent study confirms, opioids continue to be frequently prescribed for pain, even though there are less addictive alternatives available. These medications aren’t that expensive so are frequently covered by insurance.

The M2 blog, Coverage Drives Treatment: The Case of Pain explains how insurance companies seem to prefer to cover what is inexpensive, and perhaps less effective, at least when it comes to opioids for pain.

Confounding situations like this are when we understand why an overhaul of the health care system is appealing to some. It would be an incredible opportunity to step back and create a new system that approaches all situations – obesity, pain, everything – from the perspective of longer term effectiveness. Ultimately this would reduce health care system costs overall, as less time (and money) would be spent covering up symptoms of something that is likely to cause greater expense down the road.

But in order to do this, we’d have to face who we think deserves what kind of care. These decisions are baked in to the system we have and rarely discussed. 2019 is around the corner. Should we start this conversation in the new year?

Opioid Epidemic and Drug Addiction Crisis Require Bold Action, but Also a Huge Amount of Money

By |2019-07-12T17:35:29+00:00August 9th, 2017|Health care spending, Uncategorized|

Opioid Epidemic and Drug Addiction Crisis Require Bold Action, but Also a Huge Amount of Money

On March 29, 2017, President Donald J. Trump signed an Executive Order establishing the President’s Commission on Combating Drug Addiction and the Opioid Crisis. The Commission is led by New Jersey Governor Chris Christie (R), and will issue a final report with its findings and recommendations by October 1, 2017.

The commission issued an interim report July 31, 2017, and many news headlines focused on either what the commission called “the first and most urgent recommendation,” which was to urge the President to declare a national emergency (which U.S. Health and Human Services Secretary Dr. Tom Price told reporters on August 8, 2017, the President has no plans to do immediately), or, some of the more alarming facts about drug addiction, for example:

  • “Only 10 percent of the nearly 21 million citizens with a substance use disorder (SUD) receive any type of specialty treatment.”
  • “With approximately 142 Americans dying every day, America is enduring a death toll equal to September 11th every three weeks. (Emphasis in original).

In addition to some key findings, the interim report included areas for further consideration (to be included in the final report) and nine key recommendations, summarized as follows:

  1. Declare a national emergency.
  2. Rapidly increase treatment capacity.
  3. Mandate prescriber education initiatives.
  4. Immediately establish and fund a federal incentive to enhance access to Medication Assisted Treatment (MAT).
  5. Improve access to naloxone.
  6. Prioritize funding and manpower to quickly develop fentanyl detection sensors.
  7. Enhance interstate data sharing among state-based prescription drug monitoring programs (PDMPs).
  8. Ensure that information about SUDs be made available to medical professionals.
  9. Enforce the Mental Health Parity and Addiction Equity Act (MHPAEA).

The 10-page report includes a broad range of ideas, as it should, considering the process the commission used:

“In addition to conducting phone calls with Governors and their teams in all 50 states, we also held a listening session with bi-partisan members of Congress, and key cabinet members of your Administration. Individual Commission members have organized “listening sessions” and solicited recommendations from treatment providers, addiction psychiatrists and other physicians, data analysts, professional medical and treatment societies, medical educators, healthcare organizations, pharmacoepidemiologists, and insurance providers. Outreach also has been made to scientists with broad expertise in pain, addiction biology and treatment.”

“The first public meeting of the Commission was held on June 16th at the White House, and was a great success. The Commission members heard comprehensive public testimony by nine leading nonprofits, and have received more than 8,000 comments from the public, including comments from at least 50 organizations.”

It makes sense the commission was able to access so many voices of experience. There are lots of experts out there, and lots of previous recommendations, including one of the most recent, the 413-page Surgeon General’s Report on Alcohol, Drugs, and Health, Facing Addiction In America, published in 2016 under the Obama administration.

Show Me the Money

Ideas aren’t really the problem though. The real sticking point is money. How much money is needed to address what is likely a national emergency?

The Obama administration, the Trump administration, and our current Congress have all proposed some numbers.

The Obama administration’s President’s FY 2017 Budget included more than $1 billion over two years just for “expanding access to treatment for prescription drug abuse and heroin use.”

President Trump’s first budget, for FY 2018, proposed nearly $30 billion for drug control efforts, including for treatment and prevention efforts.

In the middle of negotiating Obamacare repeal and replace this summer, the Senate made changes to the Better Care Reconciliation Act that went from providing $2 billion to $45 billion over 10 years for substance abuse treatment and recovery.

And yet another estimate for caring for those who are already addicted was pegged at $183 billion over 10 years by Dr. Richard G. Frank, a Professor of Health Economics in at Harvard Medical School.

Addressing the opioid epidemic and drug addiction crisis can’t be about the politics of the Obama budget versus the Trump budget, or President Trump’s commission versus former President Obama’s Surgeon General’s Report on Alcohol, Drugs, and Health, Facing Addiction In America.

“If this scourge has not found you or your family yet, without bold action by everyone, it soon will,” exhorts the interim report.

We have plenty of ideas. We know what we need to do in order to save lives. But what we need to do won’t come cheap. The sooner we get to that conversation, the sooner we will be able to act boldly.

Opioid Abuse: State Prescription Drug Monitoring Programs Help Reduce Overdose Death Rates

By |2017-10-09T01:57:06+00:00April 10th, 2017|Uncategorized|

Opioid Abuse: State Prescription Drug Monitoring Programs Help Reduce Overdose Death Rates

In 2015, the director of the National Institute on Drug Abuse, Dr. Nora Volkow, “told a group of Kentucky journalists and others at the Foundation for a Healthy Kentucky Health Journalism Workshop” that it is “possible to decrease the over-prescription of opioids, but” she said, “the solutions aren’t ‘sexy.’”

For example, to address the opioid epidemic in the U.S., some states have implemented policies to curb inappropriate opioid prescribing. These policies include, for example: mandatory provider use of prescription drug monitoring programs (PDMPs), and pain clinic laws that feature requirements such as registration of pain clinics with the state, physician ownership of the clinics, prescribing restrictions, and record-keeping requirements.

A recent study published in Health Affairs found that “combined implementation of mandated provider review of state-run prescription drug monitoring program data and pain clinic laws reduced opioid amounts prescribed by 8 percent and prescription opioid overdose death rates by 12 percent.”

The study results “suggest that some opioid prescribing policies had intended effects on opioid prescribing and overdose death rates.”
“We found that mandated review of prescription drug monitoring program data combined with pain clinic laws was significantly associated with both decreased amounts of opioids prescribed and with decreased prescription opioid overdose deaths,” the authors state.

As for potential effects of these policies on heroin overdose death rates, the study notes that “publications in mainstream media and in the scientific literature have advanced the idea that opioid prescribing policies have unintentionally driven demand for heroin (a drug with similar effects) as people search for ‘a cheaper, more accessible high.’” However, the study “did not find any evidence to support the concern that these opioid prescribing policies result in increased heroin-related overdose deaths. However, additional factors, including increased heroin supply, a population already widely exposed to prescription opioids, and increased mixing of highly potent illicitly manufactured fentanyl with heroin, are likely to continue to pose daunting challenges to the prevention of heroin overdose deaths.”

“This combination of policies was effective, but broader approaches to address these coincident epidemics are needed,” said Deborah Dowell, senior medical advisor at the Centers for Disease Control & Prevention’s (CDC) National Center for Injury Prevention and Control.

One step forward is better than none, boring and unsexy as those solutions might be.

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